1997年畢業(yè)于清華大學(xué), 化學(xué)工程與工藝專業(yè)，學(xué)士；

2000年畢業(yè)于上海大學(xué), 環(huán)境科學(xué)與工程專業(yè)，碩士；

2006年畢業(yè)于美國(guó)俄亥俄州立大學(xué),化學(xué)工程專業(yè)，博士

      2006.8-2008.8, 美國(guó)俄亥俄州NSF 納米科學(xué)與工程中心, 助理研究工程師；

      2008.9-2013.3, 美國(guó)俄亥俄州BioLOC LLC., 資深研究員；

      2013.7-至今，華東理工大學(xué)，副教授

1.  高強(qiáng)韌蛋白多尺度組裝及纖維性能提升，國(guó)家重點(diǎn)研發(fā)計(jì)劃課題，2024-11，87萬(wàn)，子課題負(fù)責(zé)人，在研。

2. 骨界面高誘骨活性涂層的制備，2023-12，40萬(wàn)元，主持，項(xiàng)目開(kāi)發(fā)，在研。

3.  國(guó)家重點(diǎn)研發(fā)計(jì)劃戰(zhàn)略性國(guó)際科技創(chuàng)新合作重點(diǎn)專項(xiàng)，生物可吸收高分子基納米活性材料及植入器械制備技術(shù)，2024, 694萬(wàn)，課題負(fù)責(zé)人，已結(jié)題。

4. 中國(guó)科學(xué)院-威高研究發(fā)展計(jì)劃攻關(guān)項(xiàng)目，【2017】005號(hào)，骨誘導(dǎo)型鈦合金牙種植體的研制，238萬(wàn)元，主持，已結(jié)題。

  5. 上海市2018年度“科技創(chuàng)新行動(dòng)計(jì)劃”國(guó)際學(xué)術(shù)合作交流項(xiàng)目，兼具抗菌性和骨誘導(dǎo)性涂層的研制及其生物活性調(diào)控的研究，2021-03，49萬(wàn)元，主持，已結(jié)題。

  6. 國(guó)家自然科學(xué)基金面上項(xiàng)目，新型骨誘導(dǎo)型降解涂層的研制及其生物活性調(diào)控的機(jī)制研究,，2019-12，62萬(wàn)元，主持，已結(jié)題。

  7. 國(guó)家自然科學(xué)基金面上項(xiàng)目，基于趨化因子/BMP-2骨再生材料的構(gòu)建及其協(xié)同促進(jìn)成骨機(jī)制，2018-12，80萬(wàn)元，參與，已結(jié)題。

  8. 上海市自然科學(xué)基金項(xiàng)目, 微納尺度的鈦合金表面特性與骨形態(tài)發(fā)生蛋白微觀結(jié)構(gòu)和活性的研究, 2017-09, 10萬(wàn)元，主持，已結(jié)題。

  9. 生化檢測(cè)光盤用于食品檢測(cè), 江蘇省國(guó)際合作項(xiàng)目，2014-12，500萬(wàn)元，參與，已結(jié)題。

公開(kāi)及授權(quán)專利

     - 劉昌勝, 何宏燕, 翟龍玉, 林世琦. 具有核殼結(jié)構(gòu)的硫醇化海藻酸鹽微球及其制備方法和應(yīng)用, CN202410290493.0, 2024年3月14日

     - 史春寶，趙素麗，陳良軻，劉昌勝，許奎雪，何宏燕. 一種具有高誘骨活性的3D打印髖臼杯涂層及其制備方法, CN202410557108.4, 2024年8月13日

     - 何宏燕，王豐，金莉莉，彭程. 一種用于原位檢測(cè)炎癥環(huán)境的多參數(shù)SERS活性微針，CN115399756A，2022年11月29日

     - 劉昌勝，何宏燕，金莉莉，張鈿. Preparation method for Microneedle Patch，US20230091503A1，2023年3月23日

     - 劉昌勝，何宏燕，李春旺，楊梓鶴.一種高誘骨活性牙種植體涂層及其制備方法，ZL 202210068086.6，2022年4月19日

     - 劉昌勝, 何宏燕, 金莉莉, 張鈿. 一種微針貼片的制備方法. 專利號(hào)：ZL 202011598079.4

     - 劉昌勝, 喬忠乾, 何宏燕. 生物醫(yī)用活性鈦及其合金植入材料的表面改性方法. 專利號(hào)：ZL 201710211909.5

     - 余波，李利，何宏燕.一種新型酶聯(lián)免疫生化光盤監(jiān)測(cè)系統(tǒng)，專利號(hào)：ZL201210420985.4

出版書(shū)籍及章節(jié)

    - 第8章 生物醫(yī)用陶瓷骨水泥 收編于中文專著《生物醫(yī)用陶瓷》978-7-03-074544-6, 科學(xué)出版社，2023.

             - He H，Liu C*，Stem cell differentiation mediated by biomaterials/surfaces收編于專著《Polymeric Biomaterials for Tissue Regeneration》，Spring出版，@ 2016 & 2023.

             - Liu C, He H，英文專著Developments and Applications of Calcium Phosphate Bone Cements, Spring出版, 2017.

            - Guan J, He H, Yu B, Lee L J*, Polymeric nanoparticles and nanopore membranes for controlled drug and gene delivery, 收編于專著《Biomed Nanostructures》， Wiley出版，pp115-137, 2008.

      - Jin L, Wang Z, Peng C, He M, Wang F, He H*, Liu CS*.  Microneedle-assisted melittin-chondroitin sulfate administration for the transdermal therapy of rheumatoid arthritis, Advanced Healthcare Materials, 2025, 2400543.

      - Gu Z, Zhao D, He H*, Wang Z, SERS-based microneedle biosensor for in situ and sensitive detection of tyrosinase, Biosensors, 2024(202).

      - He M, Jin L, Wang F, Liu C, He H*, Simple, ultrasensitive detection of   superoxide anion radical mutations in melanoma mice with SERS microneedles, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy，2024 (124292).

      - Jin L, He M, Chen Y, Liu C*, He H*. Reverse milling–sputtering technology to develop scalable microneedle patches for analgesia, Materials Today Communications, 2023(106611).

      - Peng C, Jin L, Wang F*, Yang H*, He H *. Laser transparent multiplexed SERS microneedles for in situ and real-time detection of inflammation. Biosensors and Bioelectronics 225:115079, 2023.

      - Sha D, Tang S, Dong Z, Chen K, Wang N, Liu C, Ling X*, He H*, Yuan Y*. Wearable, antibacterial, and self-healable modular sensors for monitoring joints movement ultra-sensitively. European Polym J 180:111617, 2022.

      - Liu Y, Wang J, Jiang M, Li Y, Zhang Q*，He H.* Osteoindu,ctive hybrid hydrogel membranes for in situ bone regeneration in hyperglycemia, Colloids and Surfaces B: Biointerfaces 214:112450, 2022.

      - Li Y, Guo X, Dong S, Zhu T, Chen Y, Zhao S, Xie G, Jiang J*, He H*, Liu C, Zhao J*. A triple-coated ligament graft to facilitate ligament-bone healing by inhibiting fibrogenesis and promoting osteogenesis. Acta Biomaterialia, 115:160-175, 2020.

      - Li Y, Wu J, He H*, Liu C*, Zhao J.* Chondroitin sulfate-immobilized polyethylene terephthalate with ECM-mimetic immunoregulatory function for achieving in vivo osseointegration. J. Mater. Chem. B, 7:7756-7770, 2019.

      - 何宏燕，郜彭陽(yáng)，喬忠乾，屈雪，劉昌勝*。鈦金屬表面微納結(jié)構(gòu)協(xié)同抗菌肽的抗菌性能研究，中國(guó)修復(fù)重建外科雜志，2018.

      - Qin J, He H*, Zhang W, Chen F, Liu C*.Effective incorporation of rhBMP-2 on implantable titanium disks with microstructures by using electrostatic spraying deposition. RSC Advances, 6: 51914-51923, 2016.

      - Yang Y, Zhao X, Wang L, Wang F*, He H*, Wang X. Photo-polymerization of monomer crystals producing thermo-responsive micropatterns to direct cell growth and cell selective harvest．Polym. 74(1):150-158, 2015.

      - Zhang W, He H, Tian Y, Gan Q, Zhang J, Yuan Y*, Liu C*. Calcium ion-induced formation of β-sheet/-turn structure leading to alteration of osteogenic activity of bone morphogenetic protein-2. Scientific Report 5:12694-12700, 2015.

      - He H, Luedke E, et al., A naonoporous cell-therapy device with controllable biodegradation for long-term drug release. J Control Rel. 165(3): 226-233, 2013.

      - Wang F, He H(co-first), etc.  Micropatterned thermoresponsive surfaces by polymerization of monomer crystals: modulating cellular morphology and cell substrate interactions. Analy Chem. 84(21): 9439- 9445, 2012.

      - He H, Grignol V, et al.  Use of a Nanoporous Biodegradable Miniature Device to Regulate Cytokine Release for Cancer Treatment, J Control Rel. 151, 239-245, 2011.

      - He H, Yuan Y, Wang W, Chiou N-R, Epstein A J, and Lee L J, Design and testing of a CD-like biochip for enzyme-linked immunosorbent assay. Biomicrofluidics 3, 1-17, 2009.

      - Yuan Y, He H, and Lee L J, Protein A-based antibody immobilization onto polymeric microdevices for enhanced sensitivity of enzyme-linked immunosorbent assay. Biotech Bioeng. 102, 891-901, 2009.

      - Yen C, He H, Lee L J, and W. Ho, Synthesis and characterization of polycaprolactone nanoporous membranes for biomedical applications. J Mem Sci.343, 180-188, 2009.

      - Zhang X, He H(co-first author), Yen C, Ho W, and Lee L J, A biodegradable, immunoprotective, dual nanoporous capsule for cell based therapies. Biomaterials 29, 4253-4259, 2008.

      - Guan J, He H, Lee L J，and Hansford D J, Fabrication of particulate reservoir-containing, capsule-like, and self-foldable polymer microstructures for drug delivery. Small 3, 412-418, 2007.

      - He H, Li L,and Lee L J, Photopolymerization and structure formation of methacrylic acid based hydrogels in water/ethanol mixture. Polym. 47, 1612-1619, 2006.

      -  He H, Guan J, and Lee L J, Oral delivery devices based on self-folding hydrogels. J Control Rel.110(2), 339-346, 2006.

      - Guan J, He H, Hansford D J, and Lee L J, Self-folding hydrogel three-dimensional microstructures.J Phy Chem B. 109(49), 23134-23137, 2005.

      - He H, Cao X, and Lee L J, Design of a novel hydrogel-based intelligent system for controlled drug release. J Control Rel.95, 391-402, 2004.

科研獲獎(jiǎng)

        上海市2023年技術(shù)發(fā)明特等獎(jiǎng)：載生長(zhǎng)因子(rhBMP-2)高活性骨修復(fù)體的創(chuàng)制及臨床應(yīng)用，排名6.